Specific Mechanism and Application of Exosomes for Promoting Skin Tissue Repair after Injury
Author(s)
Jian Wang1,2, Naishuo Zhu1,2
Corresponding Author:
Jian Wang
Affiliation(s)
1Anling (Shanghai) Biotechnology Co., Ltd, Shanghai, 201500, China
2Oriental Beauty Valley Institute of Regenerative Medicine, Shanghai, 201500, China
Abstract
Skin has important physiological functions, such as protecting the body, sweating, feeling body temperature regulation, etc. Skin is very important for the health of the body. It can not only maintain the stability of the internal environment, but also directly or indirectly participate in various functional activities of the body. Because the skin is in direct contact with the outside world, it is vulnerable to external pressure or diseases and other factors, resulting in damage to epidermis, mucosa or tissue. In order to accelerate the healing of skin wounds, mesenchymal stem cells can be selected to repair skin injuries. Using the paracrine of mesenchymal stem cells, exosomes, the main component of mesenchymal stem cells, can regulate the formation of new blood vessels and promote cell proliferation, thus playing a role in repairing skin damage. The specific mechanism and application of exosomes in promoting skin repair and healing are still improving, and exosomes play a key role in skin tissue repair.
Keywords
skin tissue; Repair after injury; Exocrine body; Specific mechanism; Application
Cite This Paper
Jian Wang, Naishuo Zhu. Specific Mechanism and Application of Exosomes for Promoting Skin Tissue Repair after Injury. International Journal of Frontiers in Medicine (2023), Vol. 5, Issue 8: 34-39. https://doi.org/10.25236/IJFM.2023.050804.
References
[1] Liu Ziwei, Shi Quan, Wang Situo, Xu Juan. Research progress of exosomes derived from mesenchymal stem cells in skin injury repair [J]. Journal of PLA Medical College, 2022,43 (8): 896-900.
[2] Cheng Yansiwei, Song Guanbin. Mesenchymal stem cells and skin repair [J]. Journal of Biomedical Engineering, 2021,(38): 387-392.
[3] Li Man, Zhu Wei, Zhang Haiping. Research progress of exosomes of mesenchymal stem cells from different sources in skin injury repair [J]. Chinese Journal of Injury and Repair (Electronic Edition), 2021, Vol.16 (6): 515-519.
[4] Zhang Guowei, Wang Long, Deng Zhifeng. Research progress on the mechanism of repairing tissue injury by exosomes derived from MSCs [J]. China Journal of Repair and Reconstruction Surgery, 2016,30(04):499-503.
[5] Sun Xuan, Mao Nianyu, Liu Mingzhu, Dong Chuanming. Research progress of exosomes derived from mesenchymal stem cells in skin injury repair [J]. Systematic Medicine, 2019,4(16): 196-198.
[6] Han Rui, lin li, Wang Runqing, Hou Zongliu.Role and application prospect of exosomes derived from mesenchymal stem cells in regulating immune function[J]. China Tissue Engineering Research, 2019,23(17): 2762-2769.
[7] Li Shuangshuang and Du Chunyang.Characteristics and functions of exosomes from different cells[J]. International Journal of Pharmaceutical Research, 2019,46(6): 411-417.
[8] Shen Zhiming, Yuan Lei, Lu Yi, Shi Hongcan.Research progress on the role of exosomes of mesenchymal stem cells in wound repair and regeneration[J]. Chinese Journal of Trauma, 2022, 38(2):182-186.
[9] Guo Jia, Ding Qionghua, Liu Ze, Lv Siyi, Zhou Quancheng, Gao Yuhua, Bai Chunyu.Biological characteristics and immune regulation of exosomes derived from mesenchymal stem cells[J]. China Tissue Engineering Research, 2022,26(7):1141-1150.
[10] Poltavtseva RA,Poltavtsev AV,Lutsenko GV,et al. Myths reality and future of mesenchymal stem cell therapy[J].Cell Tissue Res,2019,375(3):563-574.
[11] Medhat D，Rodríguez CI，Infante A.Immunomodulatory effects of MSCs in bone healing[J].Int J Mol Sci,2019,20(21):5467.
Address: No. 1788, West Huifeng Road, Fengxian District, Shanghai, China
phone: 02160133720
